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Cat. No.: HY-142094

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NSD3-IN-2

NSD3-IN-2 is a potent NSD3 inhibitor with an IC₅₀ value of 17.97 μM. NSD3-IN-2 inhibits the growth and proliferation of non-small cell lung cancer cell lines H460, H1299 and H1650 with anti-cancer activity.

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CAS No.: 675190-57-5
화학식: C₁₇H₁₅N₅OS
분자량:337.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

NSD3-IN-2 Chemical Structure

CAS No.: 675190-57-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

All Histone Methyltransferase Isoforms :

In Vitro

NSD3-IN-2 (compound C6) (30 μM; 48 h) inhibits H3K36me3 expression in H460, H1299, H1560 cells^[1].
NSD3-IN-2 (50 μM; 7-16 d) inhibits cell proliferation of H460, H1299, H1560 cells while failing to inhibit A549 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 675190-57-5
분자량 337.40
화학식 C₁₇H₁₅N₅OS
SMILES

S=C1NC2=C(N)N=CN=C2N1CCOC3=C4C=CC=CC4=CC=C3
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Piao Lianhua, et al. Application of compound C6 as histone methyltransferase NSD3 inhibitor: China, CN109223794[P].2019-01-18.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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NSD3-IN-2

All Histone Methyltransferase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

NSD3-IN-2 Related Classifications

HY-142094 Related Classifications