1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Kynuramine dihydrobromide

Kynuramine dihydrobromide, an endogenously occurring amine, is a fluorescent substrate of plasma amine oxidase.

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Kynuramine dihydrobromide Chemical Structure

Kynuramine dihydrobromide Chemical Structure

CAS No. : 304-47-2

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Description

Kynuramine dihydrobromide, an endogenously occurring amine, is a fluorescent substrate of plasma amine oxidase[1][2].

In Vitro

Kynuramine dihydrobromide inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro[2].
Kynuramine dihydrobromide has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries[2].
Kynuramine dihydrobromide (20 μg/mL) causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Kynuramine dihydrobromide (0.064-8 μg; ICV; single does) facilitates lordosis behavior in estrogen-primed ovariectomized rats[3].
Kynuramine dihydrobromide (1.25-5.0 mg/kg; i.v.; single does) increases heart rate and blood pressure in rats[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats[3].
Dosage: 0.064, 0.32, 1.6 or 8 μg.
Administration: Intraventricular injection; single does.
Result: Produced facilitation of lordosis behavior.
Animal Model: Male rats (about 200g)[4].
Dosage: 1.25, 2.5 and 5.0 mg/kg.
Administration: Intravenous injection; single does.
Result: Promoted heart rate and blood pressure.
Molecular Weight

326.03

Formula

C9H14Br2N2O

CAS No.
SMILES

O=C(C1=CC=CC=C1N)CCN.[H]Br.[H]Br

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Kynuramine dihydrobromide Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Kynuramine dihydrobromide
Cat. No.:
HY-119395A
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