1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Kynuramine dihydrochloride

Kynuramine dihydrochloride 

Cat. No.: HY-119395B Purity: 99.69%
Handling Instructions

Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase.

For research use only. We do not sell to patients.

Kynuramine dihydrochloride Chemical Structure

Kynuramine dihydrochloride Chemical Structure

CAS No. : 36681-58-0

Size Price Stock Quantity
1 mg USD 140 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase[1][2].

In Vitro

Kynuramine inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro[2].
Kynuramine has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries[2].
Kynuramine (20 μg/mL) frequently causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Kynuramine may serve a physiological role in the modulation of female sexual behavior[3].
Kynuramine increases heart rate and blood pressure in pithed rats[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats[3].
Dosage: 0.064-8 μg.
Administration: Intraventricular administration.
Result: Produced facilitation of lordosis behavior.
Molecular Weight

237.13

Formula

C₉H₁₄Cl₂N₂O

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (527.14 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2171 mL 21.0855 mL 42.1710 mL
5 mM 0.8434 mL 4.2171 mL 8.4342 mL
10 mM 0.4217 mL 2.1085 mL 4.2171 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.77 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.77 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Kynuramine dihydrochloride
Cat. No.:
HY-119395B
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