1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Osthenol

Osthenol (Synonyms: Ostenol)

Cat. No.: HY-N2554
Handling Instructions

Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B.

For research use only. We do not sell to patients.

Osthenol Chemical Structure

Osthenol Chemical Structure

CAS No. : 484-14-0

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Description

Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1].

IC50 & Target[1]

hMAO-A

0.26 μM (Ki)

hMAO-A

0.74 μM (IC50)

Molecular Weight

230.26

Formula

C₁₄H₁₄O₃

CAS No.

484-14-0

SMILES

O=C1C=CC2=CC=C(O)C(C/C=C(C)\C)=C2O1

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

OsthenolOstenolMonoamine OxidaseMAOcoumarinselectivecompetitivedepressionInhibitorinhibitorinhibit

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