Lyxose
Lyxose is a pentose carbohydrate that serves both as a precursor for synthesizing UDP-galactopyranose mutase inhibitors in tuberculosis research and as an inhibitor of hSGLT5-mediated mannose uptake. The content of Lyxose in the cecum of mice fed a Western-style diet decreases.
For research use only. We do not sell to patients.
- CAS No.: 65-42-9
- Formula: C5H10O5
- Molecular Weight:150.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
D-lyxose (100 mM; 30 min) acts as a low-affinity competitive inhibitor of hSGLT5-mediated mannose transport in T-Rex HEK-293 cells, with 100 mM inhibiting 50% of uptake and an estimated Ki of ≥100 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65-42-9
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Molecular Weight 150.13
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Formula C5H10O5
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SMILES
OC[C@@H](O)[C@H](O)[C@H](O)C=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ghezzi C, et al. Fingerprints of hSGLT5 sugar and cation selectivity. Am J Physiol Cell Physiol. 2014;306(9):C864-C870. [Content Brief]
[2]. Jena PK, et al. Intestinal Microbiota Remodeling Protects Mice from Western Diet-Induced Brain Inflammation and Cognitive Decline. Cells. 2022;11(3):504. Published 2022 Feb 1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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