Wasalexins A and B, new phytoalexins from wasabi: isolation, synthesis, and antifungal activity

  • Bioorg Med Chem Lett. 1999 Oct 18;9(20):3015-20. doi: 10.1016/s0960-894x(99)00523-5.
M S Pedras  1 ,  J L Sorensen ,  F I Okanga ,  I L Zaharia
Affiliations
  • 1. Department of Chemistry, University of Saskatchewan, Saskatoon, SK, Canada.
PMID: 10571166 DOI: 10.1016/s0960-894x(99)00523-5
Abstract

The chemical structure determination of two phytoalexins from wasabi (Wasabia japonica, syn. Eutrema wasabi), a plant resistant to virulent isolates of the blackleg fungus [Leptosphaeria maculans (Desm.) Ces. et de Not., asexual stage Phoma lingam (Tode ex Fr.) Desm.], as well as their synthesis and Antifungal activity towards isolates of P. lingam and P. wasabiae is reported.

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