2. Academic Validation
  3. Taxoid from the needles of the Himalayan yew Taxus wallichiana with cytotoxic and immunomodulatory activities

Taxoid from the needles of the Himalayan yew Taxus wallichiana with cytotoxic and immunomodulatory activities

  • Bioorg Med Chem Lett. 2006 May 1;16(9):2446-9. doi: 10.1016/j.bmcl.2006.01.077.
Sunil K Chattopadhyay 1,  Anirban Pal,  Prakas R Maulik,  Tanpreet Kaur,  Ankur Garg,  Suman Preet S Khanuja
Affiliations

Affiliation

  • 1 Central Institute of Medicinal and Aromatic Plants, PO CIMAP, Lucknow 221005, India. [email protected]
PMID: 16480866 DOI: 10.1016/j.bmcl.2006.01.077
Abstract

The needles of Taxus wallichiana gave a taxoid 1-hydroxy- 2-deacetoxy-5-decinnamoyl-taxinine j, whose structure has been established by spectroscopic data and confirmed by X-ray crystallography. The taxoid possesses significant cytotoxic and immunomodulatory activity.

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