Mercaptoethylguanidine (MEG) dihydrobromide
Mercaptoethylguanidine (MEG) dihydrobromide is selective inhibitor of the inducible nitric oxide synthase and peroxynitrite scavenger. Mercaptoethylguanidine (MEG) dihydrobromide has the potential for inflammatory bowel diseases research.
For research use only. We do not sell to patients.
- CAS No.: 32665-11-5
- Formula: C3H11Br2N3S
- Molecular Weight:281.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Mercaptoethylguanidine (10 mg/kg/day; ip; for 5 days) dihydrobromide ameliorates oxidative stress parameters and antioxidant enzyme activities in forty-five Sprague-Dawley rats weighing 200 to 250 g with esophagus uninjured[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 32665-11-5
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Molecular Weight 281.01
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Formula C3H11Br2N3S
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SMILES
NC(NCCS)=N.[H]Br.[H]Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. B Zingarelli, et al. Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats. J Pharmacol Exp Ther. 1998 Dec;287(3):1048-55. [Content Brief]
[2]. Ahmet Guven, et al. Mercaptoethylguanidine attenuates caustic esophageal injury in rats: a role for scavenging of peroxynitrite. J Pediatr Surg. 2011 Sep;46(9):1746-52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)