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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
mmp-8
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "mmp-8" in MCE Product Catalog:
11
7
7 Cited Publications
Synonyms: (-)-Actinonin
Target:
5
5 Cited Publications
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Forschungsgebiete:
KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC50s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.
4
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Cancer
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3
Category:
other families Flavonoids Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields
Target:
2
2 Cited Publications
Art. -Nr.: HY-P4931
CAS. Nr.: 720710-69-0
2
2 Cited Publications
Art. -Nr.: HY-19485
CAS. Nr.: 1224964-36-6
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Forschungsgebiete:
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, respectively.
2
2 Cited Publications
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Forschungsgebiete:
PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively .
1
Synonyms: mmp8-I
MMP-8 inhibitor-1 (compound 21), a hydroxamic acid derivative, is a potent MMP-8 inhibitor without significant oral bioavailability .
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Forschungsgebiete:
UK-370106 is a potent and highly selective MMP-3 (IC50 of 23 nM) and MMP-12 (IC50 of 42 nM) inhibitor with >1200-fold higher potency than MMP-1, MMP-2, MMP-9, and MMP-14, and about 100-fold than MMP-13 and MMP-8. UK-370106 potently inhibits cleavage of [ 3H]-fibronectin by MMP-3 (IC50 of 320 nM) and has little effect on keratinocyte migration in vitro .
MMP2-IN-2 (compound 42) is a potent and selective MMP-2 (matrix metalloproteinases) inhibitor, with an IC50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC50 values of 12, 23.3, and 25 μM, respectively .
Art. -Nr.: HY-RS08554
Target:
Forschungsgebiete:
MMP8 Human Pre-designed siRNA Set A contains three designed siRNAs for MMP8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-112160
CAS. Nr.: 1356992-21-6
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Forschungsgebiete:
XL-784 free base is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13, respectively .
Art. -Nr.: HY-P3699
CAS. Nr.: 202273-56-1
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Forschungsgebiete:
Art. -Nr.: HY-N1454R
CAS. Nr.: 29741-09-1
Synonyms: Apigenin 7-O-glucuronide (Standard)
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
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Art. -Nr.: HY-RS08555
Target:
Forschungsgebiete:
Mmp8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mmp8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS08556
Target:
Forschungsgebiete:
Mmp8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mmp8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-N1463R
CAS. Nr.: 29741-10-4
Synonyms: Luteolin 7-glucuronide (Standard)
Category:
other families Flavonoids Flavones Phenols Polyphenols Plants
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
