820223-77-6
Chemical Structure
PF-00356231 hydrochloride
- CAS. Nr.: 820223-77-6
- Formula:C25H21ClN2O3S
- Molecular Weight:464.96
IUPAC Name: (R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophene-2-carboxamido)propanoic acid hydrochloride
InChIKey: AEKSZORLKGTXFF-VZYDHVRKSA-N
SMILES: OC(C[C@H](C1=CC=CC=C1)NC(C2=CC(C3=CC=C(C4=CC=NC=C4)C=C3)=CS2)=O)=O.[H]Cl
Biological Activity: PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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PF-00356231 hydrochloride | 99.0% | PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively. | ||||||||||||||||||||
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