820223-77-6

PF-00356231 hydrochloride Chemical Structure
820223-77-6

Chemical Structure

PF-00356231 hydrochloride

  • CAS No.: 820223-77-6
  • Formula:C25H21ClN2O3S
  • Molecular Weight:464.96

IUPAC Name: (R)-3-phenyl-3-(4-(4-(pyridin-4-yl)phenyl)thiophene-2-carboxamido)propanoic acid hydrochloride

InChIKey: AEKSZORLKGTXFF-VZYDHVRKSA-N

SMILES: OC(C[C@H](C1=CC=CC=C1)NC(C2=CC(C3=CC=C(C4=CC=NC=C4)C=C3)=CS2)=O)=O.[H]Cl

Biological Activity: PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-114091 		PF-00356231 hydrochloride 99.0% PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively.
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