202273-56-1
Chemical Structure
TNO003
- CAS No.: 202273-56-1
- Formula:C99H144N28O20S
- Molecular Weight:2078.44
InChIKey: CHJOVJMJSNVZOK-SFLHSALASA-N
SMILES: O=C([C@H]1N(CCC1)C([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@H](CCCNC(N)=N)NC(CCCNC(C3=CC=C(C=C3)/N=N/C4=CC=C(C=C4)N(C)C)=O)=O)=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)CCC(NCCNC7=CC=CC8=C7C=CC=C8S(=O)(O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: TNO003 is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm)[1].
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TNO003 | TNO003 is a selective fluorogenic substrate for stromelysin-1 (MMP-3). TNO003 has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm). | |||||||||||||||||||||
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