The regulation of the thyroid-stimulating hormone of the anterior pituitary gland by thyroid hormone and by 9-cis-retinoic acid

  • Nutr Rev. 2002 Nov;60(11):374-7. doi: 10.1301/00296640260385919.
George Wolf  1
Affiliations
  • 1. Department of Nutritional Sciences and Toxicology, University of California, Berkeley, CA 94720-3104, USA.
PMID: 12462521 DOI: 10.1301/00296640260385919
Abstract

Thyroid-stimulating hormone, TSH, of the anterior pituitary gland is regulated by the binding of the thyroid hormone-activated thyroid receptor to the TSH gene at the same time as the binding of the 9-cis-retinoic acid-activated retinoid X receptor to the same gene. Both interactions, separately or simultaneously, can suppress and thus regulate the expression of the TSH gene.

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