1 Result for "

(4aS,8aR)-NPD-001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "(4aS,8aR)-NPD-001" in MCE Product Catalog:

Cat. No.: HY-150025
CAS No.: 2366272-43-5
Research Areas:  

Cancer

(4aS,8aR)-NPD-001 is a potent and allosteric inhibitor of DNMT3A. (4aS,8aR)-NPD-001 inhibits DNMT3A activity by disrupting protein-protein interactions. (4aS,8aR)-NPD-001 induces apoptosis of acute myeloid leukemia (AML) cell lines. (4aS,8aR)-NPD-001 induces differentiation of distinct AML cell lines including cells with mutated DNMT3A R882 .
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