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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
(R)-SL18
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "(R)-SL18" in MCE Product Catalog:
Cat. No.: HY-168951
CAS No.: 3023189-40-1
(R)-SL18 is an annexin A3 (ANXA3) degrader with a Kd value of 1.15 μM for human ANXA3. (R)-SL18 induces ANXA3 degradation via the ubiquitination pathway, shows poor degradation selectivity among annexin family proteins, and its moderate ANXA3 binding affinity correlates with off-target effects. (R)-SL18 inhibits the proliferation, migration, invasion and colony formation of cancer cells. (R)-SL18 can be used in the research of triple-negative breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
