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(S)-Niguldipine

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Nom du produit Target Áreas de investigación Chemical Structure
  • HY-101390
    (+)-Niguldipine hydrochloride

    (S)-Niguldipine hydrochloride

    		 Calcium Channel Adrenergic Receptor Cardiovascular Disease
    (+)-Niguldipine hydrochloride is a 1,4-DHP receptor ligand associated with L-type Ca 2+ channels (with Ki values of 85 pmol/L in guinea pig skeletal muscle, 140 pmol/L in brain, and 45 pmol/L in heart) as well as an α1-adrenergic receptor ligand (with a Ki value of 78 nmol/L). (+)-Niguldipine hydrochloride shows much higher binding selectivity for α1α-adrenergic receptors than for α1B-adrenergic receptors. (+)-Niguldipine hydrochloride can be used in studies related to hypertension .
    (+)-Niguldipine hydrochloride

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