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Results for "

α-thrombin

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112968
    Human protein C

    		APC Cardiovascular Disease
    Human Protein C is activated by α-thrombin or α-thrombin/thrombomodulin complex to a serine protease, namely activated protein C (APC). Human Protein C can selectively inactivate factors Va and VIIIa and is a potent anticoagulant .
    Human protein C
  • HY-114164H
    Human α-Thrombin (Lyophilized)
    5+ Cited Publications

    		 Thrombin Cardiovascular Disease
    Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers .
    Human α-Thrombin (Lyophilized)
  • HY-P4475
    Sar-Pro-Arg-pNA

    		Thrombin Cardiovascular Disease
    Sar-Pro-Arg-pNA is a chromogenic substrate of α-thrombin. Sar-Pro-Arg-pNA can be used to test α-thrombin activity .
    Sar-Pro-Arg-pNA
  • HY-162109
    Thrombin inhibitor 11

    		Thrombin Cardiovascular Disease
    Thrombin inhibitor 11 is an orally active, competitive and selective α-Thrombin inhibitor, with a Ki value of 65 nM against h-αThrombin and a Ki value of 10.3 nM against rat-derived α-thrombin. Thrombin inhibitor 11 can be used for the research of thrombotic diseases .
    Thrombin inhibitor 11
  • HY-117798
    LY 806303

    		Thrombin Cardiovascular Disease
    LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue .
    LY 806303
  • HY-112968A
    Bovine Protein C

    		APC Cardiovascular Disease
    Bovine Protein C is activated by α-thrombin or α-thrombin/thrombomodulin complex to a serine protease, namely activated protein C (APC). Bovine Protein C can selectively inactivate factors Va and VIIIa and is a potent anticoagulant .
    Bovine Protein C
  • HY-123120
    SA-152

    		Thrombin Others
    SA-152 is an organophosphorus inhibitor. SA-152 modulates the fibrinogen coagulation and TAME esterase activity of bovine α-thrombin .
    SA-152
  • HY-P5889
    Thrombin receptor peptide ligand

    		Thrombin Cardiovascular Disease
    Thrombin receptor peptide ligand is a thrombin receptor antagonist peptide that can be used as an antithrombotic agent .
    Thrombin receptor peptide ligand
  • HY-165360
    JJ1

    		Thrombin Cardiovascular Disease
    JJ1 is a selective α-thrombin inhibitor with a Ki of 0.019 μM. JJ1 directly binds to the active site of α-thrombin to block its catalytic activity. JJ1 exhibits antithrombotic effects and prolongs activated partial thromboplastin time, prothrombin time, and tail bleeding time in mice. JJ1 can be used for the research of thrombotic diseases .
    JJ1
  • HY-164251
    RWJ-671818

    		Thrombin Cardiovascular Disease
    RWJ-671818 is an orally active inhibitor of human α-thrombin with a Ki of 1.3 nM. RWJ-671818 can be studied in research on venous and arterial thrombosis .
    RWJ-671818

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