RWJ-671818
RWJ-671818 is an orally active inhibitor of human α-thrombin with a Ki of 1.3 nM. RWJ-671818 can be studied in research on venous and arterial thrombosis.
For research use only. We do not sell to patients.
- CAS No.: 252271-49-1
- Formula: C18H23F2N7O3
- Molecular Weight:423.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 252271-49-1
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Molecular Weight 423.42
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Formula C18H23F2N7O3
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SMILES
O=C(CN1C(C(NCC(F)(C2=CC=CC=C2)F)=NC=C1C)=O)NCCONC(N)=N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lu, T., et al., (2010). Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif. Journal of medicinal chemistry, 53(4), 1843-1856. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)