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Results for "

Pro-Leu

" in MedChemExpress (MCE) Product Catalog:

22

Inhibitors & Agonists

3

Fluorescent Dyes

28

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131498

    Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

    Fluorescent Dye MMP Cancer
    MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
    MOCAc-PLGL(Dpa)AR
  • HY-P4931
    Mca-KPLGL-Dap(Dnp)-AR-NH2
    1 Publications Verification

    MMP Cancer
    Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)
    Mca-KPLGL-Dap(Dnp)-AR-NH2
  • HY-107663A

    Pro-Leu-Gly-NH2 TFA; Melanostatin TFA

    Dopamine Receptor Neurological Disease
    MIF-1 TFA (Melanostatin), an endogenous brain peptide, is a potent dopamine receptor allosteric modulator. MIF-1 TFA inhibits melanin formation. MIF-1 TFA blocks the effects of opioid receptor activation to modulate the analgesic effects. MIF-1 TFA accesses from the blood to the CNS by directly crossing the blood-brain barrier (BBB) .
    MIF-1 TFA
  • HY-P0208
    [Leu31,Pro34]-Neuropeptide Y (porcine)
    1 Publications Verification

    Neuropeptide Y Receptor Neurological Disease
    [Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects .
    [Leu31,Pro34]-Neuropeptide Y (porcine)
  • HY-W009686

    L-Prolyl-L-Leucine; Pro-Leu

    Amino Acid Derivatives Others
    H-Pro-Leu-OH is a leucine derivative .
    H-Pro-Leu-OH
  • HY-P3792

    Biochemical Assay Reagents Others
    Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) is a FRET substrate of Thimet oligopeptidase. Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) can be used for the determination of Thimet oligopeptidase activity .
    Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)
  • HY-P10143

    Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt

    MMP Others
    MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties .
    MMP-2/MMP-9 Substrate
  • HY-148666

    Biochemical Assay Reagents Others
    H-Gly-Oet can be coupled with Z-Pro-Leu-OEt for the synthesis of tripeptide Z-Pro-Leu-Gly-OEt by thermolysin and α-chymotrypsin catalysis .
    H-Gly-Oet
  • HY-P2648

    N-Succinyl-AAPL-p-nitroanilide

    Aminopeptidase Endocrinology
    Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia .
    Suc-Ala-Ala-Pro-Leu-pNA
  • HY-P3120

    MMP Fluorescent Dye Others
    Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2, upon cleavage by MMP-14, releases 7-methoxycoumarin-4-acetyl (Mca) (Ex/Em = 328/420 nm).
    Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2
  • HY-107663

    Pro-Leu-Gly-NH2; Melanostatin

    Dopamine Receptor Neurological Disease
    MIF-1 (Melanostatin), an endogenous brain peptide, is a potent dopamine receptor allosteric modulator. MIF-1 inhibits melanin formation. MIF-1 blocks the effects of opioid receptor activation to modulate the analgesic effects. MIF-1 accesses from the blood to the CNS by directly crossing the blood-brain barrier (BBB) .
    MIF-1
  • HY-N8743

    A 65190; Cyclo-(Leucyl-Prolyl)

    Endogenous Metabolite Cancer
    Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer .
    Cyclo(Pro-Leu)
  • HY-153613

    Ac-Pro-Leu-Val-Glu(OMe)-CH2F

    Cathepsin Cancer
    Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl m-FMKs, is a Cats inhibitor. Ac-PLVE-FMK can be used for the research of cancer .
    Ac-PLVE-FMK
  • HY-163315

    Keap1-Nrf2 AMPK Metabolic Disease
    YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active .
    YPLP
  • HY-137793

    MMP Cancer
    Pro-Leu-Gly-NHOH hydrochloride is an inhibitor of MMP-8 .
    Pro-Leu-Gly-NHOH hydrochloride
  • HY-W010873

    Amino Acid Derivatives Others
    Z-Pro-Leu-Gly-OEt is a tripeptide .
    Z-Pro-Leu-Gly-OEt
  • HY-W009686F

    Fluorescent Dye Others
    5-FAM-Pro-Leu-OH is a biological active peptide. (Used as MMP fluorescent reference standard)
    5-FAM-Pro-Leu-OH
  • HY-P2608

    Fluorescent Dye Others
    DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is the substrate for matrix metalloproteinase MMP-1, with a Km of 26.61 μM. DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH is utilized as fluorescence probe for detecting protein activity .
    DNP-Pro-Leu-Ala-Leu-Trp-Ala-Arg-OH
  • HY-P4937

    MMP Cancer
    NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys-(DMC)-NH2 is an substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3) and can be easily detected at Abs/Em=350/465 nm .
    NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys-(DMC)-NH2
  • HY-P4905

    MMP Cancer
    Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.85*10 5 M -1s -1, and poor substrate of other MMPs with the exception of MMP13 (kcat/Km = 0.53*10 5 M -1s -1) and MMP9 (0.33*10 5 M -1s -1) .
    Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2
  • HY-P2682

    MMP Metabolic Disease
    MMP-8/MMP-26 Fluorogenic substrate (DNP-Pro-Leu-Ala-Tyr-Trp-Ala-Arg) is a matrix metalloproteinase-8 (MMP-8) fluorogenic substrate. MMP-8/MMP-26 Fluorogenic substrate can be used for the research of atherosclerosis, pulmonary fibrosis, and sepsis .
    MMP-8/MMP-26 Fluorogenic substrate
  • HY-P3120A

    MMP Fluorescent Dye Others
    Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 TFA is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 TFA, upon cleavage by MMP-14, releases 7-methoxycoumarin-4-acetyl (Mca) (Ex/Em = 328/420 nm).
    Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 TFA

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