YPLP
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active.
For research use only. We do not sell to patients.
- CAS No.: 2414391-44-7
- Formula: C25H36N4O6
- Molecular Weight:488.58
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All AMPK Isoforms
More
Biological Activity
YPLP (10-50 mg/kg, i.g. for 4 weeks) improves ATP levels and energy metabolism through phosphorylation of AMPK and promotion of AMPK proteins in fatigue ICR mice[1].
YPLP (10-50 mg/kg, i.g. for 4 weeks) regulates expressions of differential abundance proteins (DAPs), participates in the protein biosynthesis/degradation, muscle dynamics, and nuclear transport process to regulate muscle function in fatigue mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:ICR mice[1]
-
Dosage:10-50 mg/kg/d
-
Administration:i.g. for 4 weeks
-
Result:Increased levels of Nrf2, ATP, pAMPK and decreased levels of Keap1.
Chemical Information
-
CAS No. 2414391-44-7
-
Molecular Weight 488.58
-
Formula C25H36N4O6
-
Sequence
Tyr-Pro-Leu-Pro
-
Sequence Shortening
YPLP
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz