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Cat. No.: HY-N8743

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Cyclo(Pro-Leu)

(Synonyms: A 65190; Cyclo-(leucyl-prolyl))

Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer.

For research use only. We do not sell to patients.

CAS No.: 5654-86-4
Formula: C₁₁H₁₈N₂O₂
Molecular Weight:210.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cyclo(Pro-Leu) Chemical Structure

CAS No.: 5654-86-4

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Sample (0.1mg)

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

Cyclo(Pro-Leu) (A 65190) is an active metabolite. Cyclo(Pro-Leu) can be isolated from Streptomyces sp. BM8. Cyclo(Pro-Leu) can be used for the research of cancer^[1].

IC₅₀ & Target

Microbial Metabolite

All Endogenous Metabolite Isoforms :

In Vitro

Cyclo(Pro-Leu) (compound 7) (1.23 μg/mL-300 μg/mL; 48 h) has cytotoxic activity for HT-29, MCF-7, A375, K562, and NCM460 cell lines with IC₅₀ values of 101.56 μM, 78.78 μM, 51.13 μM, 21.72 μM and 775.86 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 5654-86-4
Molecular Weight 210.27
Formula C₁₁H₁₈N₂O₂
Synonyms

A 65190; Cyclo-(leucyl-prolyl)
Structure Classification
- Alkaloids
- Other Alkaloids
Initial Source
- Microorganisms
Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shengsheng Lu, et al. Secondary Metabolites with Cytotoxic Activities from Streptomyces sp. BM-8 Isolated from the Feces of Equusquagga. Molecules. 2021 Dec 13;26(24):7556. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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