[Leu31,Pro34]-Neuropeptide Y (porcine)

Name: [Leu31,Pro34]-Neuropeptide Y (porcine)
Brand: MedChemExpress
SKU: HY-P0208
Rating: 4.5 (1 reviews)

製品番号: HY-P0208 純度: 99.39%: Data Sheet SDS COA 取扱説明書
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[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

カスタムペプチド

[Leu31,Pro34]-Neuropeptide Y (porcine) 構造式

CAS 番号 : 125580-28-1

容量	価格（税別）	在庫状況	数量
5 mg	$390	在庫あり	Estimated Time of Arrival: December 31
10 mg	$530	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

顧客検証

•bioRxiv. 2024 May 10.

Neuropeptide Y Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

NPY Y₁ receptor NPY Y₂ receptor NPY Y₄ receptor NPY Y₅ receptor

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

[Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects^[1]^[2].

IC₅₀ & Target^[1]

NPY Y₁ receptor

体内実験

[Leu31,Pro34]-Neuropeptide Y (porcine) displaces radiolabeled NPY from cells that express Y1 receptors in a series of human neuroblastoma cell lines and on rat PC-12 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

4222.63

分子式

C₁₉₀H₂₈₆N₅₄O₅₆

CAS 番号

125580-28-1

Appearance

Solid

Color

White to off-white

Sequence

Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

Sequence Shortening

YPSKPDNPGEDAPAEDLARYYSALRHYINLLTRPRY-NH2

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Sealed storage, away from moisture
Powder	-80°C	2 years
	-20°C	1 year
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

H₂O : ≥ 100 mg/mL (23.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.2368 mL	1.1841 mL	2.3682 mL
5 mM	0.0474 mL	0.2368 mL	0.4736 mL
10 mM	0.0237 mL	0.1184 mL	0.2368 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.39%

Select Batch:

データシート (284 KB) SDS (252 KB)

COA (258 KB) RP-HPLC (110 KB) MS (198 KB) Elemental Analysis Report (118 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Fuhlendorff J, et, al. [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist. Proc Natl Acad Sci U S A. 1990 Jan;87(1):182-6. [Content Brief]

[2]. Kokare DM, et, al. Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats. Brain Res. 2005 May 10;1043(1-2):107-14. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.2368 mL	1.1841 mL	2.3682 mL	5.9205 mL
	5 mM	0.0474 mL	0.2368 mL	0.4736 mL	1.1841 mL
	10 mM	0.0237 mL	0.1184 mL	0.2368 mL	0.5920 mL
	15 mM	0.0158 mL	0.0789 mL	0.1579 mL	0.3947 mL
	20 mM	0.0118 mL	0.0592 mL	0.1184 mL	0.2960 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.