Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)

Cat. No.: HY-P3792 Purity: 99.33%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) is a FRET substrate of Thimet oligopeptidase. Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) can be used for the determination of Thimet oligopeptidase activity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) Chemical Structure

CAS No. : 185698-23-1

Size	Price	Stock	Quantity
1 mg	USD 185	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 385	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 620	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Description

Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) is a FRET substrate of Thimet oligopeptidase. Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp) can be used for the determination of Thimet oligopeptidase activity^[1].

Molecular Weight

892.91

Formula

C₄₂H₅₂N₈O₁₄

CAS No.

185698-23-1

Appearance

Solid

Color

Light yellow to yellow

Sequence Shortening

Mca-PLGPk(Dnp)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (111.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1199 mL	5.5997 mL	11.1993 mL
5 mM	0.2240 mL	1.1199 mL	2.2399 mL
10 mM	0.1120 mL	0.5600 mL	1.1199 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.33%

Select Batch:

Data Sheet (280 KB) SDS (252 KB)

COA (263 KB) RP-HPLC (112 KB) MS (217 KB)

Handling Instructions (2659 KB)

References

[1]. Cummins PM, et al. Zinc coordination and substrate catalysis within the neuropeptide processing enzyme endopeptidase EC 3.4.24.15. Identification of active site histidine and glutamate residues. J Biol Chem. 1999 Jun 4;274(23):16003-9. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1199 mL	5.5997 mL	11.1993 mL	27.9983 mL
	5 mM	0.2240 mL	1.1199 mL	2.2399 mL	5.5997 mL
	10 mM	0.1120 mL	0.5600 mL	1.1199 mL	2.7998 mL
	15 mM	0.0747 mL	0.3733 mL	0.7466 mL	1.8666 mL
	20 mM	0.0560 mL	0.2800 mL	0.5600 mL	1.3999 mL
	25 mM	0.0448 mL	0.2240 mL	0.4480 mL	1.1199 mL
	30 mM	0.0373 mL	0.1867 mL	0.3733 mL	0.9333 mL
	40 mM	0.0280 mL	0.1400 mL	0.2800 mL	0.7000 mL
	50 mM	0.0224 mL	0.1120 mL	0.2240 mL	0.5600 mL
	60 mM	0.0187 mL	0.0933 mL	0.1867 mL	0.4666 mL
	80 mM	0.0140 mL	0.0700 mL	0.1400 mL	0.3500 mL
	100 mM	0.0112 mL	0.0560 mL	0.1120 mL	0.2800 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)185698-23-1OthersFRET substrateThimet oligopeptidasepeptideInhibitorinhibitorinhibit

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Mca-Pro-Leu-Gly-Pro-D-Lys(Dnp)

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