Search Result

Results for "

SDH

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (4) Aldose Reductase (1) Aminotransferases (Transaminases) (1) Antibiotic (3) Apoptosis (8) Bacterial (4) Bcl-2 Family (1) Biochemical Assay Reagents (2) Cannabinoid Receptor (1) Carnitine Palmitoyltransferase (CPT) (1) Caspase (1) Drug Intermediate (4) Environmental Pollutants (2) Fungal (55) Insecticide (2) Keap1-Nrf2 (2) Mitochondrial Metabolism (6) MMP (2) NOD-like Receptor (NLR) (2) P2Y Receptor (3) Parasite (3) Phosphatase (1) Reactive Oxygen Species (ROS) (7) Reference Standards (5) Small Interfering RNA (siRNA) (8) Succinate Dehydrogenase (28) α-synuclein (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (3) Endocrinology (1) Infection (63) Inflammation/Immunology (8) Metabolic Disease (9) Neurological Disease (5)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (4) siRNAs (8)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1787

Dimethyl malonate Maximum Cited Publications 9 Publications Verification	Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-113298

Citraconic acid 4 Publications Verification Methylmaleic acid	NOD-like Receptor (NLR) Keap1-Nrf2 Reactive Oxygen Species (ROS)	Cardiovascular Disease Inflammation/Immunology
Citraconic acid (Methylmaleic acid) is an orally active inhibitor targeting the NLRP3 inflammasome and Keap1-Nrf2 pathway. Citraconic acid reduces reactive oxygen species (ROS) generation by inhibiting succinate dehydrogenase (SDH) activity. Citraconic acid also modifies the conformation of Keap1 protein, relieves its inhibition of Nrf2, promotes antioxidant gene expression, and inhibits NLRP3 activation and the release of pro-inflammatory factors such as IL-1β and IL-18. Citraconic acid has anti-inflammatory and antioxidant activities, can reduce oxidative stress and cell pyroptosis, improve tissue damage, and can be used for the research of inflammation-related diseases such as acute renal ischemia-reperfusion injury. Citraconic acid is an isomer of Itaconic acid (HY-Y052) .

HY-N7114A

Chloramphenicol succinate sodium 3 Publications Verification	Bacterial P2Y Receptor Succinate Dehydrogenase Drug Intermediate	Infection Inflammation/Immunology
Chloramphenicol succinate sodium is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC₅₀ of 1.585 nM. Chloramphenicol succinate sodium serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate sodium exerts a significant inhibitory effect on colitis. Chloramphenicol succinate sodium can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease .

HY-W008151

Diphenyl Phosphate	Mitochondrial Metabolism Carnitine Palmitoyltransferase (CPT)	Metabolic Disease
Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of *SDH* (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases .

HY-118980

Sorbitol dehydrogenase-IN-1	Aldehyde Dehydrogenase (ALDH)	Metabolic Disease
Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC₅₀ s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol .

HY-Y0284

Diethyl phthalate 2 Publications Verification	Environmental Pollutants Biochemical Assay Reagents Apoptosis Aminotransferases (Transaminases) Phosphatase	Endocrinology
Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, *SDH, and ALT* in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .

HY-17520

Penthiopyrad 1 Publications Verification MTF-753	Environmental Pollutants Fungal	Infection
Penthiopyrad (MTF-753) is a carboxamide Fungicide. Penthiopyrad inhibits *SDH. Penthiopyrad exhibits broad-spectrum antifungal activity, being effective not only against Basidiomycetes, but also against Ascomycetes* and Deuteromycetes. Penthiopyrad inhibits the mycelial growth of Alternaria mali, Botrytis cinerea, Monilinia mali, Rhizoctonia solani and Sclerotinia sclerotiorum on PDA medium, with EC₅₀ values ranging from <0.4 ppm to 0.34 ppm and MIC values ranging from 6.6 ppm to 47.9 ppm .

HY-139983

SDH-IN-1 1 Publications Verification	Fungal	Infection
SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against *S. sclerotiorum* (EC₅₀ of 0.14 mg/L) .

HY-148921

SDH-IN-2	Fungal	Infection
SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC₅₀ values of 3.82-9.81 μg/mL for all the fungi . SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-E70398

Sorbitol dehydrogenase L-Iditol dehydrogenase; Polyol dehydrogenase; SDH	Biochemical Assay Reagents	Metabolic Disease
Sorbitol dehydrogenase (L-Iditol dehydrogenase) is an oxidoreductasea and catalyses the conversion of sorbitol to fructose with NAD ⁺ as the coenzyme. Sorbitol dehydrogenase catalyses pH-dependent redox reactions between NAD ⁺/NADH and sorbitol/fructose. Sorbitol dehydrogenase is implicated in diabetic complications and is a biomarker of drug-induced liver injury. Sorbitol dehydrogenase can be used for the research of diabetes and liver injury .

HY-164605

(6S)-CP-470711	Aldehyde Dehydrogenase (ALDH)	Metabolic Disease
(6S)-CP-470711 (Compound 8) is an inhibitor for sorbitol dehydrogenase, that inhibits human and rat *SDH* with IC₅₀ of 19 nM and 27 nM. (6S)-CP-470711 ameliorates the Streptozotocin (HY-13753)-induced diabetes in rats models .

HY-149876

SDH-IN-5	Fungal	Infection
SDH-IN-5 (compound 7d) is a potent succinate dehydrogenase (SDH) inhibitor, with an IC₅₀ of 3.293 μM. SDH-IN-5 is also exhibits antifungal activity, with an EC₅₀ of 0.046 μg/mL against R. solani. SDH-IN-5 could significantly inhibit the growth of R. solani in rice leaves with excellent protective and curative efficacies .

HY-178801

SDH-IN-39	Succinate Dehydrogenase Fungal	Infection
SDH-IN-39 (Compound A16) is a *SDH* inhibitor, with an IC₅₀ value of 6.83 μg/mL. SDH-IN-39 is also an antifungal agent. SDH-IN-39 shows antifungal activity against Rhizoctonia solani (EC₅₀ of 1.49 μg/mL), G. zeae, C. gloeosporioides, S. sclerotiorum and M. oryzae .

HY-178778

SDH-IN-38	Fungal	Infection
SDH-IN-38 (Compound IIIe) is a Succinate dehydrogenase inhibitor. SDH-IN-38 is an antifungal agent, with an EC₅₀ value of 0.009 μg/mL against R. solani mycelia. SDH-IN-38 inhibits mycelial growth by affecting mycelial respiration. SDH-IN-38 induces cellular senescenc and reduces mitochondrial membrane potential in mycelia .

HY-178799

SDH-IN-37	Succinate Dehydrogenase Fungal	Infection
SDH-IN-37 (Compound A37) is a potent *SDH* inhibitor, with an IC₅₀ value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC₅₀ values of 0.0144, 0.882 and 1.99 μg/mL, respectively .

HY-178495

SDH-IN-36	Mitochondrial Metabolism Reactive Oxygen Species (ROS) Apoptosis	Cancer
SDH-IN-36 (Compound 17) is a derivative of alpha-D-tocopherol. SDH-IN-36 increases ROS and induces apoptosis by inhibiting SDHC and blocking electron transfer. SDH-IN-36 can inhibit the proliferation of various tumor cells, such as SSK4 (GI₅₀ = 0.156 µM), SSNU638 (GI₅₀ = 0.659 µM), and SKATOIII (GI₅₀ = 0.490 µM) cells. SDH-IN-36 can significantly inhibit tumor growth. SDH-IN-36 can be used for research on cancers such as gastric cancer .

HY-149323

SDH-IN-4	Fungal	Infection
SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC₅₀ value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC₅₀ value of 0.23 μg/mL .

HY-164698

CP-470711	Aldehyde Dehydrogenase (ALDH)	Neurological Disease Metabolic Disease
CP-470711 is an orally active and potent and selective sorbitol dehydrogenase (SDH) inhibitor with an IC₅₀=10 nM for human SDH and IC₅₀=17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy .

HY-W272811

Camphorsulfonate sodium	Drug Intermediate Fungal	Infection
Camphorsulfonate sodium is an organic synthesis intermediate. Camphorsulfonate sodium can be used for synthesis of derivatives with SDH inhibitory activity through scaffold hopping. Camphorsulfonate sodium is also an organocatalyst that can be used as a pore-forming additive for modulating the porosity of the graphene film. Camphorsulfonate sodium can be used for binder-free porous graphene film and fungicide research .

HY-178469

SDH-IN-35	Fungal	Infection
SDH-IN-35 (Compound A17) is a potent succinate dehydrogenase (SDH) inhibitor with antifungal activity (EC₅₀=11.9 μM). SDH-IN-35 is promising for research of agricultural fungicide .

HY-172804

SDH-IN-26	Succinate Dehydrogenase Fungal Apoptosis	Infection
SDH-IN-26 (Compound C3) is a succinate dehydrogenase (SDH) inhibitor. SDH-IN-26 exhibits significant inhibitory activity against multiple phytopathogenic fungi, such as Rhizoctonia solani and Botrytis cinerea, with an EC₅₀ value of 0.270 μg/mL against Rhizoctonia solani. SDH-IN-26 damages the integrity of the fungal cell membrane, increases membrane permeability, disrupts cell structure, and reduces the number of mitochondria, thus affecting the normal growth of mycelia. SDH-IN-26 leads to a decrease in mitochondrial membrane potential, and induces cell apoptosis. SDH-IN-26 is promising for research of plant diseases caused by fungi .

HY-159481

SDH-IN-17	Succinate Dehydrogenase Fungal	Infection Inflammation/Immunology
SDH-IN-17 (compound C32), a hydrazide-containing flavonol derivative, is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 8.42 μM. SDH-IN-17 can occupy the active site and form strong interactions with the key residues of SDH. SDH-IN-17 exhibits antifungal activity against Rhizoctonia solani (EC₅₀=0.170 μg/mL). SDH-IN-17 disrupts the normal growth of hyphae by affecting the structural integrity of the cell membrane and cellular respiration. SDH-IN-17 has the potential for plant disease control research .

HY-155004

SDH-IN-3	Antibiotic Fungal	Infection
SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC₅₀ of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research .

HY-172777

SDH-IN-25	Succinate Dehydrogenase Fungal Reactive Oxygen Species (ROS) MMP	Infection
SDH-IN-25 is a succinate dehydrogenase (SDH) inhibitor (IC₅₀ = 4.82 mg/L). SDH-IN-25 exhibited broad-spectrum and potent antifungal activity. SDH-IN-25 mimics the interaction pattern of commercial fungicide Fluxapyroxad (HY-135549) through binding to *SDH* amino acid residues (TRP173, TYR58, and ARG43). SDH-IN-25 can induce hyphal morphology, interfere with respiratory metabolism by binding to complex II, generate reactive oxygen species (ROS), and affect mitochondrial membrane potential (MMP) in mycelia. SDH-IN-25 can be studied in research for agricultural disease control .

HY-178050

SDH-IN-30	Fungal Succinate Dehydrogenase	Infection
SDH-IN-30 (Compound 7m) is a Succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 0.34 μM. SDH-IN-30 has potent antifungal activities against Rhizoctonia solani and Sclerotinia sclerotiorum with EC₅₀ s of 0.004 and 0.028 μg/mL. SDH-IN-30 also has remarkable protective and curative efficacies against R. solani and significantly inhibits S. sclerotiorum growth on oilseed rape leaves by damaging the fungal cell structure. SDH-IN-30 can be used for fungal infections like rice sheath blight (RSB) and sclerotinia stem rot (SSR) research .

HY-120183

Harzianopyridone	Fungal	Infection
Harzianopyridone is a compound that can be isolated from Trichoderma harzianum. Harzianopyridone is a succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 80 nM. Harzianopyridone has antifungal, antibacterial, and herbicidal activities .

HY-106371

Siccanin	Antibiotic Fungal	Infection
Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC₅₀=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi .

HY-Y1787R

Dimethyl malonate (Standard)	Reference Standards Apoptosis	Neurological Disease
Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis .

HY-W008151R

Diphenyl Phosphate (Standard)	Mitochondrial Metabolism Reference Standards	Metabolic Disease
Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases .

HY-N7114

Chloramphenicol succinate	Bacterial Drug Intermediate P2Y Receptor Succinate Dehydrogenase	Infection Inflammation/Immunology
Chloramphenicol succinate is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC₅₀ of 1.585 nM. Chloramphenicol succinate serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate exerts a significant inhibitory effect on colitis. Chloramphenicol succinate can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease .

HY-149601

SDH-IN-8	Fungal	Infection
SDH-IN-8 (compound G40) is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 27 nM for porcine SDH. SDH-IN-8 has fungicidal properties .

HY-149600

SDH-IN-7	Fungal	Infection
SDH-IN-7 (compound G28) is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 26 nM for porcine SDH. SDH-IN-7 has fungicidal properties .

HY-172212

SDH-IN-23	Insecticide Reactive Oxygen Species (ROS)	Infection
SDH-IN-23 (Compound B21) is an *SDH* inhibitor. SDH-IN-23 exhibits excellent nematicidal activity. SDH-IN-23 can inhibit the feeding, reproduction, and embryonic development of nematodes. Meanwhile, SDH-IN-23 exerts a lethal effect on nematodes by triggering oxidative stress, causing intestinal damage, and inhibiting *SDH*, among other mechanisms .

HY-158321

SDH-IN-15	Fungal Succinate Dehydrogenase	Infection
SDH-IN-15 (Compound 5e) is an inhibitor of succinate dehydrogenase (SDH) (IC₅₀=2.04 μM). SDH-IN-15 has significant antifungal activity. SDH-IN-15 blocks the mitochondrial respiratory chain of the fungus through inhibition of SDH, resulting in fungal death .

HY-157459

SDH-IN-11	Fungal	Infection
SDH-IN-11 (compound A7) is a *SDH* inhibitor, and shows inhibitory effect on nematode feeding, reproductive ability, and egg hatching. SDH-IN-11 promotes the oxidative stress of nematodes and causes intestinal damage to nematodes. SDH-IN-11 inhibits the activity of succinate dehydrogenase (SDH) in nematodes .

HY-161504

SDH-IN-14	Fungal Succinate Dehydrogenase	Infection
SDH-IN-14 (Compound Z2) is an inhibitor of succinate dehydrogenase (SDH). SDH-IN-14 has antifungal activity (EC₅₀=2.7 μg/mL) against B.cinerea. SDH-IN-14 acts by disrupting the integrity of the cell wall and cell membrane .

HY-155700

SDH-IN-6	Fungal	Infection
SDH-IN-6 (compound 6i) is a potent succinate dehydrogenase (SDH) inhibitor. SDH-IN-6 has antifungal activity against Valsa mali with an EC₅₀ value of 1.77 mg/L .

HY-173264

SDH-IN-24	Parasite Insecticide	Infection
SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC₅₀ for *SDH* is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of *SDH* to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields .

HY-172362

SDH-IN-22	Succinate Dehydrogenase Fungal	Infection
SDH-IN-22 (Compound SEZC7) is the inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 16.6 μM. SDH-IN-22 exhibits antifungal activity that inhibits Magnaporthe grisea with an EC₅₀ of 0.5 mg/L .

HY-161375

SDH-IN-13	Fungal	Infection
SDH-IN-13 (Compound 5IIIh) is a *SDH* inhibitor (IC₅₀: 13.7 μg/mL) and an antifungal agent .

HY-178457

SDH-IN-34	Succinate Dehydrogenase Fungal	Infection
SDH-IN-34 is a Succinate Dehydrogenase inhibitor with antifungal activity. SDH-IN-34 can be used for the research of infection .

HY-159486

SDH-IN-18	Succinate Dehydrogenase Fungal	Infection
SDH-IN-18 (Compound 3a) is an inhibitor for succinate dehydrogenase (SDH) with an IC₅₀ of 8.70 mg/L. SDH-IN-18 destroys fungal morphology and reproduction, exhibits antifungal activity against Rhizoctonia solani and Sclerotinia sclerotiorum with EC₅₀ of 0.48 and 1.4 mg/L .

HY-174390

SDH-IN-29	Fungal Succinate Dehydrogenase	Infection
SDH-IN-29 (Compound A33) is a *SDH* inhibitor with an IC₅₀ of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC₅₀s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively). SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew .

HY-179287

SDH-IN-42	Fungal Mitochondrial Metabolism Reactive Oxygen Species (ROS)	Infection
SDH-IN-42 (Compound D28) is a *SDH* (IC₅₀: 5.38 μg/mL) inhibitor and antifungal agent. SDH-IN-42 exerts antifungal activity against R. solani by disrupting mycelial morphology, increasing cell membrane permeability, inducing the production and accumulation of ROS, and impairing mitochondrial function .

HY-156270

SDH-IN-9	Bacterial	Infection
SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC₅₀ of 0.93 μg/mL .

HY-163911

SDH-IN-19	Fungal Antibiotic	Infection
SDH-IN-19 (compound A13) is a fungicide, with an EC₅₀ value of 0.83 μg/mL against Rhizoctonia solani. SDH-IN-19 can be used in antifungal research of crops .

HY-174831

SDH-IN-28	Fungal Succinate Dehydrogenase	Infection
SDH-IN-28 is a succinate dehydrogenase inhibitor with an IC₅₀ value of 2.65 mg/L. SDH-IN-28 demonstrates broad-spectrum fungicidal efficacy, with EC₅₀ values of 0.21 (Valsa mali), 0.95 (Botrytis cinerea), 0.64 (Rhizoctonia solani), 1.33 (Fusarium graminearum), and 0.66 mg/L (Gaeumannomyces graminis). SDH-IN-28 effectively prevents V. mali infection in apples .

HY-176413

SDH-IN-27	Fungal	Infection
SDH-IN-27 (Compound Q18) is a succinate dehydrogenase inhibitor (SDHI) (IC₅₀: 9.7 mg/L). SDH-IN-27 induces mycelial morphology changes and lipid peroxidation, and exhibits antifungal activity against C. camelliae (EC₅₀: 6.0 mg/L). SDH-IN-27 is an ergosterol biosynthesis inhibitor (EBI) that binds to the active site of CYP51, ultimately leading to cell death of pathogenic fungi .

HY-149653

SDH-IN-10	Fungal	Infection
SDH-IN-10 is a potent succinate dehydrogenase inhibitor (SDHI) with antifungal effects .

HY-163284

SDH-IN-12	Succinate Dehydrogenase Fungal	Infection
SDH-IN-12 (compound 9b) is a succinate dehydrogenase inhibitor, which exhibits activity against S. sclerotiorum and C. arachidicola, with EC₅₀s of 0.97 and 2.07 μM, respectively. SDH-IN-12 reveals no significant herbicidal activity against monocotyledonous and dicotyledonous plants .

Cat. No.	Product Name	Type

HY-119976R

Boscalid (Standard)

Biochemical Assay Reagents

Boscalid (Standard) is the analytical standard of Boscalid. This product is intended for research and analytical applications. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis .

Host:	Mouse (8) Rabbit (4)
Reactivity:	Human (12) Rat (4) Mouse (6)
Application:	IHC-P (10) ICC/IF (6) IP (3) WB (6) FC (9) ELISA (6)
Isotype:	IgG (3) IgG1 (6) IgG/Kappa (1) IgG2a (2)
Conjugation:	Non-conjugated (12)
Clonality:	Monoclonal (8) Recombinant (2)
Modification:	Unmodified (8)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84184

	SDHB Antibody (YA3881) IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP	IHC-P, FC, ELISA	Human
	SDHB Antibody (YA3881) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDHB.

HY-P84184A

	SDHB Antibody (YA3881)(PBS only) IP; SDH; CWS2; PGL4; SDH1; SDH2; SDHIP	IHC-P, FC, ELISA	Human
	SDHB Antibody (YA3881) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDHB.

HY-P86391

	SDHB Antibody (YA6083) SDHB; SDH; SDH1; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur subunit of complex II; Ip	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	SDHB Antibody (YA6083) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SDHB.

HY-P81835

	SDHB Antibody (YA1580) SDHB; SDH; SDH1; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial; Iron-sulfur subunit of complex II; Ip	WB, IHC-P, IP, FC	Human, Mouse, Rat
	SDHB Antibody (YA1580) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SDHB.

HY-P88615

	SDSL Antibody (YA8299) cSDH; SDH 2; SDS-RS1; TDH	IHC-P, FC	Human
	SDSL Antibody (YA8299) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDSL.

HY-P88334

	SDS Antibody (YA8018) SDH	IHC-P, ICC/IF, FC	Human
	SDS Antibody (YA8018) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDS.

HY-P88615A

	SDSL Antibody (YA8299)(PBS only) cSDH; SDH 2; SDS-RS1; TDH	IHC-P, FC	Human
	SDSL Antibody (YA8299) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDSL.

HY-P88334A

	SDS Antibody (YA8018)(PBS only) SDH	IHC-P, ICC/IF, FC	Human
	SDS Antibody (YA8018) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SDS.

HY-P84251

	SDHA Antibody (YA3948) FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA	WB, ICC/IF, FC, ELISA	Human, Mouse
	SDHA Antibody (YA3948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDHA.

HY-P84251A

	SDHA Antibody (YA3948)(PBS only) FP; PGL5; SDH1; SDH2; SDHF; CMD1GG; MC2DN1; NDAXOA	WB, ICC/IF, FC, ELISA	Human, Mouse
	SDHA Antibody (YA3948) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to SDHA.

HY-P86640

	SDHA Antibody (YA6332) SDHA; SDH2; SDHF; Succinate dehydrogenase [ubiquinone] flavoprotein subunit; mitochondrial; Flavoprotein subunit of complex II; Fp	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	SDHA Antibody (YA6332) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SDHA.

HY-P87067

	SDHC Antibody(YA6760) CYB560 antibody; C560_HUMAN antibody; CYBL antibody; Cytochrome B large subunit of complex II antibody; Integral membrane protein CII-3 antibody; mitochondrial antibody; PGL3 antibody; QPs-1 antibody; QPs1 antibody; SDH3 antibody; CYB560 antibody; C560_HUMAN antibody; CYBL antibody; Cytochrome B large subunit of complex II antibody; Integral membrane protein CII-3 antibody; mitochondrial antibody; PGL3 antibody; QPs-1 antibody; QPs1 antibody; SDH3 antibody; SDHC antibody; succinate dehydrgenase cytochrome b antibody; succinate dehydrogenase 3, integral membrane subunit antibody; Succinate dehydrogenase complex subunit C antibody; Succinate dehydrogenase complex subunit C integral membrane protein 15kDa antibody; Succinate dehydrogenase cytochrome b560 subunit antibody; Succinate dehydrogenase cytochrome b560 subunit mitochondrial antibody; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor antibody; Succinate-ubiquinone oxidoreductase cytochrome B large subunit antibody;	WB, IHC-P	Human, Mouse, Rat
	SDHC Antibody(YA6760) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SDHC.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-148921

SDH-IN-2		Alkynes
SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC₅₀ of 0.55 μg/mL. SDH-IN-2 is also an antifungal agent. SDH-IN-2 inhibits phytopathogenic fungia with average EC₅₀ values of 3.82-9.81 μg/mL for all the fungi . SDH-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

SDH

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Antibodies

Click Chemistry

Oligonucleotides

Natural
Products