300548-99-6
300548-99-6
Chemical Structure
CP-470711
- CAS No.: 300548-99-6
- Formula:C18H26N6O2
- Molecular Weight:358.44
InChIKey: ATNZXIACLONSSN-XJFOESAGSA-N
SMILES: C[C@@H]1N(C2=NC([C@H](O)C)=NC=C2)[C@@H](CN(C3=NC([C@H](O)C)=NC=C3)C1)C
Biological Activity: CP-470711 is an orally active and potent and selective sorbitol dehydrogenase (SDH) inhibitor with an IC50=10 nM for human SDH and IC50=17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy[1].
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CP-470711 | CP-470711 is an orally active and potent and selective sorbitol dehydrogenase (SDH) inhibitor with an IC50=10 nM for human SDH and IC50=17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy. | |||||||||||||||||||||
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References
Keywords
