2 Results for "

1103508-80-0

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1103508-80-0" in MCE Product Catalog:

Cat. No.: HY-14721A
CAS No.: 1103508-80-0
Synonyms: EMD-1214063 hydrochloride
Target:  

c-Met/HGFR Autophagy

Research Areas:  

Cancer

Tepotinib (EMD-1214063) hydrochloride is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib hydrochloride inhibits c-Met phosphorylation and induces autophagy. Tepotinib hydrochloride has antitumor effects .
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-14721
CAS No.: 1100598-32-0
Purity:  99.94%
Synonyms: EMD-1214063
Target:  

c-Met/HGFR Autophagy

Research Areas:  

Cancer

Tepotinib (EMD-1214063) is an orally active and highly selective, reversible, ATP-competitive c-Met inhibitor with an IC50 of 3 nM, >200-fold selective for c-Met than IRAK4, TrkA, Axl, IRAK1, and Mer. Tepotinib inhibits c-Met phosphorylation and induces autophagy. Tepotinib has antitumor effects .
loading...
    loading...