1 Result for "

1111188-09-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1111188-09-0" in MCE Product Catalog:

Cat. No.: HY-174143
CAS No.: 1111188-09-0
Target:  

Apoptosis

Research Areas:  

Cancer

EXO1-IN-1 is a human exonuclease 1 (EXO1) inhibitor (IC50 = 15.7 μM). EXO1-IN-1 inhibits DNA end resection, promotes the accumulation of DNA double-strand breaks, and triggers S-phase polyamylation. EXO1-IN-1 induces apoptosis (Apoptosis) in BRCA1-deficient breast cancer cells. EXO1-IN-1 suppresses the growth of BRCA1-deficient breast cancer xenografts. EXO1-IN-1 can be used in research related to BRCA1-deficient breast cancer .
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