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1309272-50-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1309272-50-1" in MCE Product Catalog:

Cat. No.: HY-17514S2
CAS No.: 1309272-50-1
Synonyms: R51211-d9
Itraconazole-d9 is the deuterium labeled Itraconazole . Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor .
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