1 Result for "

1335113-30-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1335113-30-8" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-W395779
CAS No.: 1335113-30-8
Target:  

Filovirus

Research Areas:  

Infection

EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM .
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