1 Result for "

1360550-05-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1360550-05-5" in MCE Product Catalog:

Cat. No.: HY-12995A
CAS No.: 1360550-05-5
Target:  

FLAP

Research Areas:  

Inflammation/Immunology

(S)-BI 665915 is an orally active oxadiazole-containing 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50 of 1.7 nM for FLAP binding. (S)-BI 665915 inhibits FLAP functional in human whole blood with an IC50 of 45 nM. (S)-BI 665915 demonstrates an excellent cross-species agent metabolism and pharmacokinetics (DMPK) profile and a dose-dependent inhibition of LTB4 production .
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