1 Result for "

162412-70-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "162412-70-6" in MCE Product Catalog:

Cat. No.: HY-123744
CAS No.: 162412-70-6
Purity:  99.92%
PD-156707 is an orally active, nonpeptide and selective Endothelin-A receptor antagonist. PD-156707 binds to human ET-A and ET-B receptors with Ki values of 0.17 nM and 133.8 nM, respectively. PD-156707 shows reversal of established chronic hypoxic pulmonary hypertension in rats. PD-156707 can be used for the study of diseases associated with abnormal ET-A receptor activation, particularly pulmonary hypertension, stroke, and heart failure .
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