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16378-21-5

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1 Results for "16378-21-5" in MCE Product Catalog:

Cat. No.: HY-W683866
CAS No.: 16378-21-5
Research Areas:  

Neurological Disease

Piroheptine is a muscarinic acetylcholine receptor (mAChR) antagonist and dopamine reuptake inhibitor. Piroheptine blocks the high-affinity dopamine transport system, prevents MPP + uptake into dopaminergic neurons, and exerts anticholinergic activity. Piroheptine completely prevents MPTP (HY-W114750)-induced loss of striatal dopamine and DOPAC, and increases striatal dopamine levels. Piroheptine can be used in studies related to Parkinson's disease .
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