1 Result for "

1714984-32-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "1714984-32-3" in MCE Product Catalog:

Cat. No.: HY-183651
CAS No.: 1714984-32-3
Target:  

15-PGDH PGE synthase

Research Areas:  

Inflammation/Immunology

15-PGDH-IN-5 is a sulfoxide-based inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH). 15-PGDH-IN-5 exhibits great water solubility, metabolic stability, and in vivo exposure levels. 15-PGDH-IN-5 blocks the 15-PGDH-mediated irreversible oxidative degradation of PGE2 and increases the effective concentration of endogenous PGE2 in tissues, thereby exerting anti-inflammatory effects and promoting tissue repair and regeneration. 15-PGDH-IN-5 is suitable for research into tissue injury and fibrosis-related diseases, such as inflammatory bowel disease and idiopathic pulmonary fibrosis .
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