1 Result for "

1909226-00-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "1909226-00-1" in MCE Product Catalog:

Cat. No.: HY-101083
CAS No.: 1909226-00-1
Target:  

Bcl-2 Family

Research Areas:  

Cancer

BDA-366 is a potent Bcl2 antagonist (Ki = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells .
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