1 Result for "

2007971-51-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2007971-51-7" in MCE Product Catalog:

Cat. No.: HY-119316
CAS No.: 2007971-51-7
CM-414 is a brain-penetrant phosphodiesterase 5 (PDE5) and HDAC inhibitor with IC50s of 60 nM, 91 nM, 310 nM, 322 nM and 490 nM for PDE5, HDAC6, HDAC1, HDAC3 and HDAC2, respectively. CM-414 diminishes brain and tau phosphorylation (pTau) level in Tg2576 mice. CM-414 can be used for the study of Alzheimer's disease (AD) .
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