1 Result for "

2055024-54-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2055024-54-7" in MCE Product Catalog:

Cat. No.: HY-W800625
CAS No.: 2055024-54-7
Target:  

ADC Linkers

Research Areas:  

Cancer

Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
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