1 Result for "

2074702-04-6

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2074702-04-6" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-134471
CAS No.: 2074702-04-6
Purity:  98.75%
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

TNF-α-IN-2 is a potent and orally active inhibitor of tumor necrosis factor alpha (TNFα), with an IC50 of 25 nM in the HTRF assay. TNF-α-IN-2 distorts the TNFα trimer upon binding, leading to aberrant signaling when the trimer binds to TNFR1. TNF-α-IN-2 can be used for the research of rheumatoid arthritis .
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