1 Result for "

2077980-80-2

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2077980-80-2" in MCE Product Catalog:

Cat. No.: HY-101119
CAS No.: 2077980-80-2
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

GLL398 is a potent, orally bioavailable selective estrogen receptor degrader (SERD) with an IC50 value of 1.14 nM. GLL398 shows a strong dose-dependent binding to ER with a mutation at Y537S (IC50=29.5 nM). GLL398 blocks tumor growth in xenograft models of breast cancer.
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