3 Results for "

2108806-02-4

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "2108806-02-4" in MCE Product Catalog:

Cat. No.: HY-111066A
CAS No.: 2108806-02-4
Purity:  99.41%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder .
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Cat. No.: HY-111066AR
CAS No.: 2108806-02-4
JNJ-37822681 (dihydrochloride) (Standard) is the analytical standard of JNJ-37822681 (dihydrochloride). This product is intended for research and analytical applications. JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder .
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Cat. No.: HY-111066
CAS No.: 935776-74-2
Target:  

Dopamine Receptor

Research Areas:  

Others

JNJ-37822681 is a fast dissociating D2 antagonist with activity in inhibiting schizophrenia. JNJ-37822681 has high specificity for D2 receptors and is effective in animal models, inducing increased levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibiting antidepressant activity in the mouse tail suspension test, while having a good brain distribution and lower prolactin release.
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