2 Results for "

2135515-67-0

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "2135515-67-0" in MCE Product Catalog:

Cat. No.: HY-169752
CAS No.: 2135515-67-0
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

APJ receptor agonist 11 (Ex 174) is a APJ receptor agonist with IC50 values ranging from 0.01 nM to 10 nM. APJ receptor agonist 11 can be used in the study of cardiovascular diseases .
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Cat. No.: HY-145284
CAS No.: 2762567-70-2
Target:  

Apelin Receptor (APJ)

Research Areas:  

Cardiovascular Disease

APJ receptor agonist 4 is a potent and orally active agonist of apelin receptor (APJ) with EC50 and Ki of 0.06 nM and 0.07 nM respectively. APJ receptor agonist 4 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 4 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 4 leads to improved cardiac function and can be used for researching the HF disease .
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