1 Result for "

2200453-71-8

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2200453-71-8" in MCE Product Catalog:

Cat. No.: HY-159941
CAS No.: 2200453-71-8
Target:  

α-synuclein

Research Areas:  

Neurological Disease

tau-0N4R-IN-1 (Compound 6T) is an BBB-penetrable inhibitor of tau 0N4R oligomerization. tau-0N4R-IN-1 effectively inhibits the fibrosis of tau 0N4R, 2N3R, and 2N4R, exhibits an anti-seeding effect on tau in vitro, reduces the oligomerization of α-syn dose-dependently, and prevents formation of α-syn inclusions. tau-0N4R-IN-1 is stable in mouse microsomes and reduces plaques in brain tissues from AD patients. tau-0N4R-IN-1 has good pharmacokinetic properties in mice .
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