1 Result for "

2227279-84-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2227279-84-5" in MCE Product Catalog:

Cat. No.: HY-154851
CAS No.: 2227279-84-5
Purity:  98.72%
Target:  

GSK-3 CDK Tau Protein

Research Areas:  

Neurological Disease

GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. GSK-3 inhibitor 3 lowers levels of tau protein phosphorylation at S396 in a triple-transgenic mouse Alzheimer’s disease model, with IC50 of 10 nM. GSK-3 inhibitor 3 can be used for neurological disease research .
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