3 Results for "

2227455-78-7

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "2227455-78-7" in MCE Product Catalog:

Cat. No.: HY-19617A
CAS No.: 2227455-78-7
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-1 hydrochloride is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 hydrochloride potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity .
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Cat. No.: HY-19617B
CAS No.: 2753348-63-7
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-1 TFA is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 TFA potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 TFA displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity .
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Cat. No.: HY-19617
CAS No.: 1625677-63-5
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-1 (compound 24) is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity .
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