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2249814-82-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2249814-82-0" in MCE Product Catalog:

Cat. No.: HY-13238S2
CAS No.: 2249814-82-0
Synonyms: S/GSK1349572-d5
Dolutegravir-d5 is deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM) .
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