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2256762-71-5

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2256762-71-5" in MCE Product Catalog:

Cat. No.: HY-40354S
CAS No.: 2256762-71-5
Synonyms: Tasocitinib-13C3; CP-690550-13C3
Tofacitinib- 13C3 (Tasocitinib- 13C3; CP-690550- 13C3) is the 13C-labeled Tofacitinib (HY-40354). Tofacitinib (Tasocitinib) is an orally active, blood-brain barrier permeable selective inhibitor of JAK1/JAK3. Tofacitinib blocks the JAK-STAT/NF-κB signaling pathway, inhibits cytokine signal transduction, phosphorylation of STAT1/STAT5, and suppresses innate and adaptive immune responses. Tofacitinib can be used in research related to major depressive disorder, rheumatoid arthritis, pulmonary diseases, systemic lupus erythematosus, and immune-mediated liver injury .
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