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2319668-87-4

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1 Results for "2319668-87-4" in MCE Product Catalog:

Tibesaikosaponin V
Tibesaikosaponin V
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Cat. No.: HY-N11507
CAS No.: 2319668-87-4
Synonyms: TKV
Category:  

Sonchus asper (L.) Hill Triterpenes Terpenoids Plants Umbelliferae

Target:  

PPAR

Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders .
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