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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
23806-24-8
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "23806-24-8" in MCE Product Catalog:
Cat. No.: HY-W004782
CAS No.: 23806-24-8
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3-Methylthiophene-2-carboxylic acid (compound 3) is a potent Pseudomonas quinolone signal system protein E (PqsE) inhibitor with a Kd of 19.6 µM and an IC50 of 40 µM. 3-Methylthiophene-2-carboxylic acid binds to the active center of PqsE and shows inhibition of the thioesterase activity. Methylthiophene-2-carboxylic acid can permeate into P. aeruginosa and affect 2,4-dihydroxyquinoline (DHQ) levels to a similar extent as deletion of the PqsE gene. 3-Methylthiophene-2-carboxylic acid can be used for cystic fibrosis research .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
