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2417097-18-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2417097-18-6" in MCE Product Catalog:

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Cat. No.: HY-145765
CAS No.: 2417097-18-6
Purity:  98.24%
JQAD1 is a EP300 PROTAC degrader. JQAD1 selectively targets EP300 and induces its degradation via the CRBN-dependent proteasomal pathway. JQAD1 reduces the levels of H3K27ac and the expression of MYCN. JQAD1 induces apoptosis (apoptosis) and inhibits cancer cell growth. JQAD1 exerts anti-neuroblastoma effects in vivo in a CRBN-dependent manner. JQAD1 can be used for the research of neuroblastoma .
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