1 Result for "

2475658-74-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2475658-74-1" in MCE Product Catalog:

Cat. No.: HY-146019A
CAS No.: 2475658-74-1
Target:  

HIV

Research Areas:  

Infection

HIV-1 inhibitor-25 (compound R-12a) is a highly potent HIV-1 reverse transcriptase, with an IC50 value of 0.1061 μM. HIV-1 inhibitor-25 has high antiretroviral activity against WT HIV-1 with an EC50 of 13.6 nM, and exhibits relatively low cytotoxicity with a CC50 of 33.13 μM in MT-4 cells. HIV-1 inhibitor-25 also has inhibitory activity against HIV-1 mutant strains (L100I, K103N, Y181C, Y188L, E138K, F227L+V106A) with EC50 of 0.1961 ~ 5.8136 μM. HIV-1 inhibitor-25 can be used for researching AIDS .
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