1 Result for "

2517855-91-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2517855-91-1" in MCE Product Catalog:

Cat. No.: HY-15495B
CAS No.: 2517855-91-1
Synonyms: (3S)-CC-930 hydrochloride
Research Areas:  

Inflammation/Immunology

(3S)-Tanzisertib (hydrochloride) ((3S)-CC-930 (hydrochloride)) is an orally active JNK inhibitor (IC50 values for JNK1, JNK2, and JNK3 are 61, 7, and 6 nM, respectively). (3S)-Tanzisertib (hydrochloride) selectively inhibits ERK1, p38α, and EGFR (IC50 = 0.48, 3.4, and 0.38 μM, respectively). (3S)-Tanzisertib (hydrochloride) inhibits LPS-induced TNFα production in an acute rat PK-PD model. (3S)-Tanzisertib (hydrochloride) can be used in idiopathic pulmonary fibrosis (IPF) research .
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