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253688-61-8

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Cat. No.: HY-145516
CAS No.: 253688-61-8
Synonyms: Ro 47-8634
Research Areas:  

Metabolic Disease

Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan (HY-A0013).1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.
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